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CARVTOP-ICD Trial

Comparative Effectiveness of Carvedilol versus Metoprolol Succinate in Heart Failure Patients with an Implantable Cardioverter Defibrillator (ICD)

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What is this study about?

This study, called the CARVTOP-ICD trial, is focused on improving care for people with heart failure who have an implantable cardioverter defibrillator (ICD). ICDs are devices that help prevent sudden cardiac death, but the treatments they deliver—especially shocks—can be stressful and affect quality of life.

Many patients with ICDs take a type of medication called a beta-blocker. Two common options are metoprolol succinate and carvedilol, but doctors don’t yet know which one is better for patients with ICDs. This study compares the two medications to see which one leads to fewer heart rhythm problems, fewer hospital visits, and a better quality of life.

Sponsored By:

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Funded By:

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Contact Us

Have questions about the CARVTOP-ICD study? We're here to help! Whether you want to know more about eligibility, study locations, or participation details, feel free to reach out.

Contact Info – Study email: contempicd.mail@heart.rochester.edu